2017 Mar/Apr 37(2):283-290.Įvaluation of the bone regeneration potential of bioactive glass in implant site development surgeries: a systematic review of the literature. Laurito D, Lollobrigida M, Gianno F, Bosco S, Lamazza L, De Biase A.
Maxillary Sinus Augmentation Using Hydraulic Pressure by Lateral Approach and Simultaneous Implant Placement: Clinicoradiographic Study.īhandari S, Thomas R, Kumar T, Shah R, Mehta DS.Īlveolar Ridge Preservation with nc-HA and d-PTFE Membrane: A Clinical, Histologic, and Histomorphometric Study. NovaBone® Dental Putty is stable at room temperature, does not require refrigeration, has a 4-year shelf-life, and appears radiodense on radiographs. It is pre-mixed, cohesive, moldable, and adaptable. It is ready to use and extremely user friendly. NovaBone® Dental Putty significantly simplifies bone graft handling and delivery. Cartridges are available in various sizes and are used in conjunction with NovaBone's® cartridge delivery system each cartridge holds 0.25 cc's or 0.5 cc’s of putty. The cartridges simplify dispensing of the graft, especially in hard-to-reach areas, thus facilitating minimally invasive techniques (and hard-to-access defects such as gaps in immediate implant placement and crestal-approach sinus lifts). NovaBone® is the only graft material in the world that is available in disposable uni-dose cartridges. NovaBone® Dental Putty is available in multiple delivery options: trays, pre-filled syringes, and a unique industry-first cartridge delivery system. In vitro gene array analysis has confirmed that when human primary osteoblasts are exposed to extracts of CPS, upregulation of several gene families occurs. These surface reactions result in an osteostimulative affect, defined as the stimulation of osteoblast proliferation in vitro as evidenced by increased DNA content and elevated osteocalcin and alkaline phosphatase levels.
After implantation, surface reactions result in absorption of the graft material, a controlled release of Si, Ca, and P ions, and concurrent new bone formation. Unlike most synthetic grafts that are only osteoconductive, bioactive NovaBone® Dental Putty also has an "osteostimulative" effect. Subsequently, the larger particles (90-710 μm) react, and being more resistant to resorption, continue the process of bone regeneration. The smaller CPS particles (32-125 μm) are more rapidly resorbed, providing the initial burst of Ca and P ions. Upon implantation, the water soluble binder is absorbed within 24 to 72 hours, creating a 3-dimensional porous scaffold that facilitates diffusion of blood and tissue fluids through the matrix. The bioactive CPS component makes up 70% of the putty by volume. The binder improves handling and aids in maintaining the space between the particles, which facilitates revascularization after implantation. It is composed of calcium phosphosilicate (CPS) particles in a bimodal size distribution combined with a polyethylene glycol and glycerine binder. To learn more about how and for what purposes Amazon uses personal information (such as Amazon Store order history), please visit our Privacy Notice.NovaBone® Dental Putty is 100% synthetic and fully resorbable.
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